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World Health Organization : Year 1998 ; World Health Organization, Emerging and Other Communicable Disease Surveillance and Control, Zoonoses, No. 98.3: Control and Prevention of Campylobacter Infections. Suggestions for the Design, Conduct and Analysis of an Epidemiological Study Aimed at Identification of Risk Factors for Campylobacter Infections in Humans

By Georg Kapperud

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Book Id: WPLBN0000155497
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Title: World Health Organization : Year 1998 ; World Health Organization, Emerging and Other Communicable Disease Surveillance and Control, Zoonoses, No. 98.3: Control and Prevention of Campylobacter Infections. Suggestions for the Design, Conduct and Analysis of an Epidemiological Study Aimed at Identification of Risk Factors for Campylobacter Infections in Humans  
Author: Georg Kapperud
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Kapperud, G. (n.d.). World Health Organization : Year 1998 ; World Health Organization, Emerging and Other Communicable Disease Surveillance and Control, Zoonoses, No. 98.3. Retrieved from http://www.worldjournal.org/


Description
Medical Reference Publication

Excerpt
1. INTRODUCTION Thermotolerant Campylobacter bacteria have been the focus of growing attention during the past decade due to the increasing frequency with which they have been isolated from humans, animals, foods, and water (1-3). The bacteria concerned are now recognized among the most important agents of enteritis in the world. Campylobacter infections are a frequent cause of morbidity both in developed and developing countries, and represent a considerable drain on economic and public health resources. Although bacteriological surveys have identified a number of possible sources of infection, there is still much uncertainty about how many of the human cases are of foodborne origin and how many occur as a result of other exposures. The relative importance of these sources can only be determined through epidemiological investigations which entail statistical analysis of case-control studies. Several such studies have been conducted in Europe and North-America in order to determine risk factors and guide preventive efforts (4-14).

Table of Contents
Table of Contents 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. Definition and selection of case-patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.1 Case definition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.2 Selection of cases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3. Definition and selection of controls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3.1 Matching criteria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3.2 Exclusion criteria . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3.3 Selection of controls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 4. Creating the questionnaire . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.1 Defining research hypotheses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.2 Formulating questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.3 Checklist for questionnaire development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 4.4 Separate questionnaires for cases and controls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4.5 Pilot study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 5. Collecting questionnaire data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 6. Data entry and validation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 7. Statistical analyses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 8. Computer programs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 9. Informed consent and confidentiality . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 10. An example: Case-control study of Campylobacter infections in Norway . . . . . . . . . 10 11. References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Appendix I: Case-Control study of campylobacteriosis. Patient Questionnaire . . . 12

 
 


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